For uptake and coverage of oral PrEP among adolescent girls and young women, this paper proposes an intervention-centric cascade framework and common lexicon of metrics. By coding indicators, the discussion of 'low' uptake can focus on achieving higher AGYW using PrEP when and where they want it. Recommended implementation research can quantify sub-groups and improve monitory systems' efficiencies in service delivery to take PrEP to AGYW to scale.